Medic and rear security member of the S.T.A.R.S. Bravo Team. Rebecca was a child genius and graduated college at the young age of 18 with exceptional grades. She has ample experience in the use of medicines and is an expert at chemistry and the manufacture of pharmaceuticals.
When at work, Rebecca wears the same beret and uniform with shoulder pads as Jill Valentine, but was outfitted with lighter gear for the mission into the Arklay Forest.
Ecliptic Express and Management Training Facility
On July 23, 1998, Chambers was dispatched with Bravo Team to investigate a series of bizarre murders in the Arklay Mountains. The team's helicopter made a forced landing in the forest due to engine difficulties. While securing the area, the S.T.A.R.S. discovered a wrecked military transport which had been carrying former Marine Billy Coen, who had been sentenced to execution for multiple murders.
Investigating further, Chambers found and boarded a train which had stalled in the forest. Billy Coen was on the train, and despite their mistrust of one another, they were forced to cooperate to survive against the various monsters which had overtaken it.
The train took Chambers and Coen to an abandoned Management Training Facility formerly operated by the Umbrella Corporation and run by founding member James Marcus. Further investigation led the pair to Marcus' private lab and to a treatment plant where they confronted and killed Marcus, who had been mutated by a queen leech. Following their escape, Chambers and Coen parted ways, with Chambers heading toward a mansion where she expected to regroup with the other S.T.A.R.S. members.
Arklay Research Facility
Rebecca Chambers took refuge in a dormitory in the mansion's guardhouse, where she was discovered by fellow S.T.A.R.S. officer Richard Aiken. Together, the two made their way back to the mansion proper, but Richard was bitten and poisoned by an enormous snake. Chambers and S.T.A.R.S. Alpha Team member Chris Redfield investigated the mansion and were eventually rescued along with two other members of Alpha Team by Alpha helicopter pilot Brad Vickers.
Upon her return to civilization, Rebecca wrote a police report detailing Billy Coen's "death". What happened to her after that is unknown.